1. Isolable hydroxamic acid-derived precursors enable carbonate-triggered nitrile oxide cycloadditions

Xin Zhang, Guangxing Gu, Yujia Zhang, and Yanchuan Zhao* 

Org. Chem. Front. 2026, doi: 10.1039/d6qo01284a 文章链接 

 

 

2. A Fluorinated Cyclorhodium Probe Enables Separation-Free ¹⁹F NMR Enantiodifferentiation of Chiral Amines and Nitriles 

Guangxing Gu, Tianci Peng, and Yanchuan Zhao* 

Anal. Chem. 2026, 98, 27558–27566. 文章链接 

 

 

 

3. An Axially Chiral Salicylaldehyde-Based ¹⁹F NMR Probe for the Enantiomeric Discrimination of Chiral Amines  

Tianci Peng, Jiajin Weng, Guangxing Gu, and Yanchuan Zhao* 

Chin. J. Org. Chem. 2026, 46, 3704–3712. 文章链接 

 

 

4. Repurposing Hypervalent Iodine: From Synthetic Reagents to Dynamic ¹⁹F NMR Probes for Chiral Discrimination 

Wenjing Bao, Jiajin Weng, Guangxing Gu, Ziyang Zhang, Yucheng Gu, and Yanchuan Zhao* 

JACS Au 2026, 6, 4550–4561. 文章链接  ACS Editors' Choice

 

 

 

5. Elucidating the Role of Halogen Bonding in Engineering Noncovalent Porous Crystals

Qi Jia, Nie Fang, Wenjie Zhu, and Yanchuan Zhao* 

Cryst. Growth Des. 2026, 26, 5888–5894 . 文章链接  

 

 

 

6. Programmable Ammonium Sequestration and Release via a Kinetically Gated Supramolecular Host

Wenjie Zhu, Jiajin Weng, Wei Zhang, Qi Jia, Haoliang Hao, Zhenchuang Xu, Yucheng Gu, and Yanchuan Zhao* 

Chin. J. Chem. 2026, 44, 3099-3105. 文章链接  

 

 

7. Revisiting Cation-π Interaction Paradigms: Confinement-Induced Unusual Trends and Implications for Reactivity Control

Zhenchuang Xu, Wenjie Zhu, Jian Wu, Wei Zhang and Yanchuan Zhao* 

CCS Chem. 2026, 8, 3137–3148. 文章链接  

 

 

8. Chiral Analysis for High-Throughput Reaction Screening: Recent Advances in Accelerating Asymmetric Catalysis Discovery

Nijia Yu, and Yanchuan Zhao* 

Chem. Eur. J. 2026, e71122.  文章链接  

 

 

9. Detection and Identification of Alkenes and Alkynes Using a ¹⁹F-Labeled NMR Probe

Zixuan Ma, Chenyang Wang, Guangxing Gu, and Yanchuan Zhao* 

Anal. Chem. 2026, 98, 13803–13809.  文章链接  

 

10. Expanding the toolbox of C-H functionalization: the emergence of DMIX-substituted hypervalent iodine reagents

Qilong Lv, and Yanchuan Zhao* 

Tetrahedron Lett. 2026, 177, 155979.  文章链接  

 

 

11. Separation-free enantiodiscrimination of chiral pesticides via dual-stereocenter ¹⁹F NMR probes for multicomponent and environmental analysis

Xin Zhang, Guangxing Gu, Jiajin Weng, Chenyang Wang, Zixuan Ma, Xiaojun Tang* and Yanchuan Zhao* 

Anal. Chim. Acta 2026, 1390, 345141.  文章链接  

 

 

12. Site-Selective Azidation of Arenes via Hypervalent Iodine-Mediated C–H Functionalization

Ziyang Zhang, Jiajin Weng, and Yanchuan Zhao* 

Org. Lett. 2026, 28, 788–793.  文章链接  

 

 

13. Harnessing dynamic recognition for enhanced NMR-based detection

Guangxing Gu, Zhenchuang Xu, Nijia Yu, and Yanchuan Zhao* 

Coord. Chem. Rev. 2026, 551, 217454. 文章链接  

 

 

14. Enantiomeric Differentiation of Chiral Diols via ¹⁹F NMR Using a Multicomponent Approach: Observing the Isotopic Influence of Boron

Zixuan Ma, Guangxing Gu, Yilin Zeng, Jiajin Weng, Wenjing Bao, and Yanchuan Zhao* 

Talanta 2026, 298, 129057. 文章链接  

 

 

15. Photocatalytic modular synthesis of functionalized cyclotetrasiloxane (D4) monomers toward tailored polysiloxanes

Shaowei Chen, Zhiqiang Fang, Xiaoqian He, Qi Jia, Yanchuan Zhao, and Xiao Shen*

Green Chem. 2026, 28, 154–158. 文章链接  

 

1. Harnessing Halogen Bonds in Porous Molecular Crystals for Efficient SF₆/N₂ Separation 

Qi Jia, Chong Zhao, Wenjie Zhu, Nie Fang, Xiao He*, and Yanchuan Zhao* 

Angew. Chem. Int. Ed. 2025, 64, e202517907.  文章链接  

 

 

2. Enantiodifferentiation of Chiral Hydroxy Acids via ¹⁹F NMR 

Yilin Zeng, Zixuan Ma, and Yanchuan Zhao* 

New J. Chem. 2025, 49, 19420–19426. 文章链接  

 

 

 

3. A Universal ¹⁹F NMR Probe for Enantiomeric Discrimination of Primary, Secondary, and Tertiary Amines

Jiajin Weng, Guangxing Gu, Wenjing Bao, and Yanchuan Zhao* 

ACS Meas. Sci. Au 2025, 5, 890–896. 文章链接  

 

 

 

4. Chiral Discrimination of Organothiols via ¹⁹F NMR and a Multicomponent Reaction

Yilin Zeng, Jiajin Weng, Guangxing Gu, Jian Wu, Byungjin Koo, and Yanchuan Zhao* 

Anal. Chem. 2025, 97, 17398–17404. 文章链接  分析人亮点介绍

 

 

5. Exploring the Interplay of Backbone Packing and Peripheral Interactions to Engineer Noncovalent Porous Crystal

Qi Jia, Nie Fang, Wenjie Zhu, Xu Zhang, and Yanchuan Zhao* 

Cryst. Growth Des. 2025, 25, 6014–6022. 文章链接  

 

 

6. A ¹⁹F-labeled Probe for the Chiral Discrimination of Thiols and Thioethers

Jiajin Weng, Guangxing Gu, Wei Zhang, Qi Jia, Yining Sun, Jian Wu, and Yanchuan Zhao* 

Angew. Chem. Int. Ed. 2025, 64, e202505700. 文章链接  化学谷亮点介绍  科研留声机亮点介绍  化学加亮点介绍  荧光超分子科学亮点介绍

 

 

7. High-Throughput ¹⁹F NMR Chiral Analysis for Screening and Directed Evolution of Imine Reductases

Shucheng Song, Chenyang Wang, Wenjing Bao, Zhenchuang Xu, Jian Wu, Liang Lin*, and Yanchuan Zhao* 

ACS Cent. Sci. 2025,11, 1094–1102. 文章链接  分析人亮点介绍  科学纵横亮点介绍

 

 

 

8. Site-Selective Nitration of Arene via Hypervalent Iodine-Mediated C–H Functionalization

Ziyang Zhang, Wenjing Bao, Guangxing Gu, Zhenjiang Liu*, and Yanchuan Zhao* 

Org. Lett. 2025, 27, 4842–4847. 文章链接  CBG亮点介绍  进击的药物化学亮点介绍

 

 

 

 

 

9. Hypervalent Iodine-Mediated Selective Monofunctionalization of Calix[4]arenes 

Haoliang Hao, Wei Zhang, Wenjie Zhu, Wenjing Bao, Guangxing Gu, and Yanchuan Zhao*

Org. Lett. 2025, 27, 4712–4717. 文章链接  CBG亮点介绍

 

 

 

10. A General Protocol for Efficient Construction of Perfluoro-tert-butyl Alkynes with (Perfluoro-tert-butyl)propiolic Acid 

 Zhiqiang Wei, Guangxing Gu, Wei Zhang, Yanchuan Zhao*, and Jinbo Hu*

Org. Chem. Front. 2025, 12, 4773–4779. 文章链接  

 

 

 

11. Transition-Metal-Free Arene C–H Functionalization for the Synthesis of Sulfoximines 

 Wenbo Zhang, XinYu Li, Yanchuan Zhao*, and Bing Gao*

Chem. Commun. 2025, 61, 6671–6674. 文章链接  RSC亮点介绍

 

 

 

12. ¹⁹F NMR-Based Lithium Sensors using ¹⁹F-Labeled Aza-crown Ethers: Regioisomeric and Substituent Effects 

 Donghyeon Lee, Yanchuan Zhao, and Byungjin Koo*

Dyes and Pigments 2025, 239, 112762. 文章链接 

 

 

 

13. Enhancing Molecular-Level Biological Monitoring with a Smart Self-Assembling ¹⁹F-Labeled Probe

Zhenchuang Xu, Chenyang Wang, Shengyuan He, Jian Wu, and Yanchuan Zhao*

Angew. Chem. Int. Ed. 2025, 64, e202417112. 文章链接 WileyChem亮点介绍  X-MOL资讯亮点介绍  CBG亮点介绍 化学深耕堂亮点介绍

 

 

14. Exploring the Chiral Match–Mismatch Effect in the Chiral Discrimination of Nitriles

Guangxing Gu, Yining Sun, Chenyang Wang, Yilin Zeng, Tianci Peng, Byungjin Koo, and Yanchuan Zhao*

Anal. Chem. 2025, 97, 1909–1916. 文章链接  

 

 

15. ¹⁹F-Labeled NMR Probes for the Detection and Discrimination of Nitrogen-Containing Analytes

Guangxing Gu, Chenyang Wang, and Yanchuan Zhao*

Synthesis 2025, 57, 1671–1689. 文章链接  

 

1. Bioinspired Ion Host with Buried and Consecutive Binding Sites for Controlled Ion Dislocation

Wenjie, Zhu, Zhenchuang Xu, Wei Zhang, Qi Jia, Haoliang Hao, Yu-Cheng Gu, and Yanchuan Zhao*

JACS Au  2024, 4, 4415–4422. 文章链接 

 

 

 

2. Synthesis of Diaryl Ethers via Hypervalent Iodine-Mediated C–H Functionalization

Chenghu Hu, Qi Jia, Wenjing Bao, Guangxing Gu, Ya Li,* and Yanchuan Zhao*

Org. Lett.  2024, 26, 7864–7868. 文章链接 CBG亮点介绍

 

 

 

3. Tailoring the Performance of ¹⁹F-Labeled Probes via Dynamic Covalent Chemistry for Improved Chiral Discrimination

Jiajin Weng, Lixian Wen, Guangxing Gu, Wenjing Bao, Jian Wu, and Yanchuan Zhao*

Anal. Chem.  2024, 96, 13551–13556. 文章链接 分析人亮点介绍

 

 

 

4. NMR-Based Chiral Discrimination of Bulky Amines with a ¹⁹F-Tagged NNO Pincer Complex

Wenjing Bao, Hongshaung Wang, Lixian Wen, Jian Wu, Yu-Cheng Gu, Xiaohui Wu,* and Yanchuan Zhao*

Anal. Chem.  2024, 96, 11448–11454. 文章链接 分析人亮点介绍

 

 

 

5. Detection and Differentiation of Amines and N-Heterocycles via Recognition Enabled Chromatographic ¹⁹F NMR

Guangxing Gu, Yinlin Zeng, Tianci Wu, Wenjing Bao, Ziyang Zhang, Jian Wu, and Yanchuan Zhao*

Eur. J. Org. Chem. 2024, 27, e202400441. 文章链接 WileyChem亮点介绍

 

 

6. A High-performance Chiral ¹⁹F-Labeled Probe with an Increased Structural Twisting

Chenyang Wang, Guangxing Gu, Wei Zhang, Jian Wu, and Yanchuan Zhao*

Chem. Commun. 2024, 60, 5082–5085. 文章链接 分析人亮点介绍 RSC亮点介绍

 

 

7. Detection and Identification of Nitrile Compounds via Recognition-Enabled Chromatographic ¹⁹F NMR

Wenjing Bao, Guangxing Gu, Jian Wu, Yu-Cheng Gu, and Yanchuan Zhao*

Anal. Chem.  2024, 96, 6463–6468. 文章链接  分析人亮点介绍

 

 

 

8. Conformational Locking as a Strategy to Reverse Ion Recognition Selectivity

Wei Zhang, Chong Zhao, Wenjie Zhu, Xiao He*, and Yanchuan Zhao*

J. Org. Chem.  2024, 89, 4037–4041. 文章链接 

 

 

 

9. Enantiodifferentiation of Chiral Diols and Diphenols via Recognition-Enabled Chromatographic ¹⁹F NMR

Yilin Zeng, Wenjing Bao, Guangxing Gu, and Yanchuan Zhao*

Magn. Reson. Lett.  2024, 4, 200112. 文章链接 分析人亮点介绍

 

 

10. Bioinspired Organic Porous Coupling Agent for Enhancement of Nanoparticle Dispersion and Interfacial Strength

Qi Jia, and Yanchuan Zhao*

ACS Appl. Mater. Interfaces 2024, 16, 6403–6413. 文章链接 科研留声机亮点介绍

 

 

 

11. Chiral Discrimination of Acyclic Secondary Amines by ¹⁹F NMR

Guangxing Gu, Chong Zhao, Wei Zhang, Jiajin Weng, Zhenchuang Xu, Jian Wu, Yingbo Xie, Xiao He*, and Yanchuan Zhao*

Anal. Chem. 2024, 96, 730–736. 文章链接  分析人亮点介绍

 

1. Layered Porous Molecular Crystals via Interdigitation-Directed Assembly

Nie Fang , Siquan Zhang, Zhenchuang Xu, Si Chen, Xu Zhang, Hui Wu, Wei Zhou, and Yanchuan Zhao*

Cell. Rep. Phys. Sci. 2023, 101508. 文章链接  Phy.Org  上海有机所微信公众号  API家亮点介绍

 

 

 

2. Improving the Sensitivity of Enantioanalysis with Densely Fluorinated NMR Probes

Yushu Jia , Lixian Wen, Wenjing Bao, Zhenchuang Xu, Jian Wu, and Yanchuan Zhao*

Anal. Chem. 2023, 95, 10362–10367. 文章链接  分析人亮点介绍

 

 

 

3. Chiral Discrimination of Nitrile Compounds Using a ¹⁹F-Labeled Palladium Probe

Guangxing Gu , Yue Yue, Chengyang Wang, Wei Zhang, Jian Wu, Ya Li*,  and Yanchuan Zhao*

Org. Lett.  2023, 25, 4819–4824. 文章链接  CBG亮点介绍

 

 

 

4. Research Progress on Organic Cation Receptors Based on Molecular Containers

Wenjie Zhu , Zhenchuang Xu, Yu-Cheng Gu, and Yanchuan Zhao*

Chin. J. Org. Chem. 2023, 43, 2991–3005. 文章链接  有机化学亮点介绍

 

 

 

5. Chirality Sensing of N-Heterocycles via ¹⁹F NMR

Guangxing Gu, Zhenchuang Xu, Lixian Wen, Jinhua Liang, Chenyang Wang, Xiaolong Wan, and Yanchuan Zhao*

JACS Au 2023, 3, 1348–1357. 文章链接   ACS Publications亮点介绍  上海有机所微信公众号

 

 

 

6. Tailoring the Recognition Property of a ¹⁹F-Labeled Gallium-Based NMR Probe: The Influence of the Metal Center

Jinhua Liang, Zhenchuang Xu, Jian Wu, and Yanchuan Zhao*

Anal. Chem. 2023, 95, 7569–7574. 文章链接 分析人亮点介绍

 

 

7. ¹⁹F-Labeled Probes for Recognition-Enabled Chromatographic ¹⁹F NMR

Zhenchuang Xu, and Yanchuan Zhao*

Chem. Rec. 2023, 23, e202300031. 文章链接

 

 

 

8. Detection and Identification of Amphetamine-Type Stimulants and Analogs via Recognition-Enabled “Chromatographic” ¹⁹F NMR.

Jiayu Jiang, Lixian Wen, Hongshuang Wang, Xiaoguang Chen,* Yanchuan Zhao,* and Xiaohui Wang*

J. Fluorine Chem. 2023, 266, 110085. 文章链接 分析人亮点介绍

 

 

 

9. ¹⁹F-labeled molecular probes for NMR-based detection

Zhenchuang Xu, and Yanchuan Zhao*

J. Fluorine Chem. 2023, 266, 110089. 文章链接

 

1. Tailoring Sensors and Solvents for Optimal Analysis of Complex Mixtures Via Discriminative ¹⁹F NMR Chemosensing. 

Chanjuan Dong, Zhenchuang Xu, Lixian Wen, Shengyuan He, Jian Wu, Qing-Hai Deng*, and Yanchuan Zhao*

Anal. Chem. 2021, 93, 2968–2973.  文章链接  X-mol亮点介绍 分析人亮点介绍

 

 

 

2. Calix[4]trap: A Bioinspired Host Equipped with Dual Selection Mechanisms.

Zhenchuang Xu, Nie Fang, and Yanchuan Zhao*

J. Am. Chem. Soc. 2021, 143, 3162–3168. 文章链接  有机所官网介绍  中科院官网转载  CBG #人物与科研#

 

 

 

3. Synthesis and Characterization of Diastereoisomeric Polyesters Derived from Bisphenols Bearing Vicinal Trifluoromethyl Groups.

Jinghuang Lv, Si Chen, Zhenchuang Xu, Siquan Zhang, Ya Li*, and Yanchuan Zhao*

Macromolecules 2021, 54, 3716–3724. 文章链接

 

 

 

4. Difluorocarbene-Mediated Cascade Cyclization: The Multifunctional Role of Ruppert–Prakash Reagent

Yanyao Cai, Wenjie Zhu, Shujuan Zhao, Chanjuan Dong, Zhenchuang Xu, and Yanchuan Zhao*

Org. Lett. 2021, 23,  3546–3551. 文章链接

 

 

5. Achieving Efficient Organic Solar Cells via Synergistically Doping Active Layers and Interfaces by a Conjugated Macrocycle.

Yan Wang, Yi Zhang, Tong Shan, Qingyun Wei, Zhenchuang Xu, Yanchuan Zhao, Jianming Yang, Qinye Bao, Hui Jin, Zaifei Ma, Hao Wei and Hongliang Zhong*

J. Mater. Chem. A, 2021, 9, 25629–25640. 文章链接

 

                                                  

1. Separation-free Enantiodifferentiation with Chromatogram-like Output. 

Yipeng Li, Lixian Wen, Huan Meng, Jinghuang Lv, Gen Luo, and Yanchuan Zhao* 

Cell Reports Physical Science , 2020, 1, 100100.  文章链接 中科院官网介绍 有机所官网介绍

 

 

 

2. Poly(o‐xylylene)s via Cobalt‐Catalyzed Reductive Polymerization. 

Si Chen and Yanchuan Zhao* 

Chin. J. Chem. 2020, 38, 952–958. 文章链接

 

 

 

3. C_sp³-C_sp³ Bond Formation Via Transition-metal Mediated and Catalyzed Reductive Homocouplings.

Si Chen and Yanchuan Zhao* 

Chin. J. Org. Chem. 2020, 40, 3078–3093.  文章链接

 

 

1. Molecular Sensors for NMR-Based Detection. 

Zhenchuang Xu, Chao Liu, Shujuan Zhao, Si Chen, and Yanchuan Zhao* 

Chem. Rev. 2019, 119 , 195–230. 文章链接

  

 

2. Waveguide-based chemo- and biosensors: complex emulsions for the detection of caffeine and proteins. 

Lukas Zeininger, Elisabeth Weyandt, Suchol Savagatrup, Kent S. Harvey, Qifan Zhang, Yanchuan Zhao, and Timothy M. Swager* 

Lab. Chip. 2019, 19, 1327–1331. 文章链接

  

 

3. Polymers with Side Chain Porosity for Ultrapermeable and Plasticization Resistant Materials for Gas Separations. 

Yuan He, Francesco M. Benedetti, Sharon Lin, Chao Liu, Yanchuan Zhao, Hong‐Zhou Ye, Troy Van Voorhis, M. Grazia De Angelis, Timothy M. Swager, Zachary P. Smith*

Adv. Mater. 2019, 31 , 1807871. 文章链接  MIT NEWS亮点介绍

  

 

4. Nonafluoro-tert-butoxylation of Diaryliodonium Salts. 

Huan Meng, Lixian Wen, Zhenchuang Xu, Yipeng Li, Jian Hao* and Yanchuan Zhao* 

Org. Lett. 2019, 21, 5216–5210. 文章链接

  

 

1. Recent advances in mechanochemical C–H functionalization reactions. 

Shujuan Zhao, Yipeng Li, Chao Liu, Yanchuan Zhao* 

Tetrahendron Lett. 2018, 59, 317–324.  文章链接           

 

 

2. Porous Organic Polymers via Ring Opening Metathesis Polymerization. 

Yanchuan Zhao, Yuan He, and Timothy M. Swager* 

ACS Marco Lett. 2018, 7 , 300–304. 文章链接     

 

 

3. Conformation of bis-nitroxide polarizing agents by multi-frequency EPR spectroscopy. 

Janne Soetbeer, Peter Gast, Joseph J. Walish, Yanchuan Zhao, Christy George, Chen Yang, Timothy M. Swager, Robert G. Griffin, and Guinevere Mathies*

Phys. Chem. Chem. Phys. 2018, 20, 25506–25517. 文章链接  

 

 

4. Iron-Catalyzed Difluoromethylation of Arylzincs with Difluoromethyl 2-Pyridyl Sulfone. 

Wenjun Miao, Yanchuan Zhao, Chuanfa Ni, Bing Gao, Wei Zhang, and Jinbo Hu* 

J. Am. Chem. Soc. 2018, 140 , 880–883.  文章链接 

 

 

5. Synthesis of 2,2-diaryl-1,1-difluoroethenes via Pd-catalyzed dehydrosulfonylative cross-coupling of α-[difluoro(phenylsulfonyl)methyl]benzyl tosylates with arylboronic acids. 

Rui Zhang, Chuanfa Ni, Yanchuan Zhao, and Jinbo Hu*

Tetrahedron 2018, 74 , 5295–5302. 文章链接 

 

 

1. Mechanochemical Synthesis of Extended Iptycenes. 

Yanchuan Zhao, Silvia V. Rocha, and Timothy M. Swager* 

J. Am. Chem. Soc. 2016, 138 , 13834–13837.  文章链接 

 

 

2. Simultaneous Identification of Neutral and Anionic Species in Complex Mixtures without Separation. 

Yanchuan Zhao, Lily Chen, and Timothy M. Swager* 

Angew. Chem. Int. Ed. 2016, 55 , 917–921.  文章链接

 

 

 

3. Bis(difluoromethyl)trimethylsilicate Anion: A Key Intermediate in Nucleophilic Difluoromethylation of Enolizable Ketones with Me₃SiCF₂H. 

Dingben Chen, Chuanfa Ni, Yanchuan Zhao, Xian Cai, Xinjin Li, Pan Xiao, and  Jinbo Hu* 

Angew. Chem. Int. Ed. 2016, 55, 12632–12636.   文章链接       

 

 

 

4. Nucleophilic Iododifluoromethylation of Carbonyl Compounds Using Difluoromethyl 2-Pyridyl Sulfone. 

Wenjun Miao, Chuanfa Ni, Yanchuan Zhao, and Jinbo Hu* 

Org. Lett. 2016, 18, 2766-2769. 文章链接        

 

 

 

1. Functionalized Metalated Cavitands via Imidation and Late‐Stage Elaboration. 

Yanchuan Zhao, and Timothy M. Swager* 

Eur. J. Org. Chem. 2015, 121,  4593-4597.  文章链接

 

 

2. Spontaneous Resolution of Julia-Kocienski Intermediates Facilitates Phase Separation to Produce Z- and E-Monofluoroalkenes.

Yanchuan Zhao, Fanzhou Jiang, and Jinbo Hu* 

J. Am. Chem. Soc. 2015, 137, 5199-5203. 文章链接

 

 

3. Simultaneous Chirality Sensing of Multiple Amines by ¹⁹F NMR. 

Yanchuan Zhao and Timothy M. Swager* 

J. Am. Chem. Soc. 2015, 137 , 3221-3224.  文章链接  ChemistryViews亮点评述  C&E NEWs亮点评述  Chem-Station亮点评述 

 

 

4. Carbonyl olefination of diaryl ketones with heteroaryl sulfoxides.

Bing Gao, Jingyu Hu, Yanchuan Zhao, Jinbo Hu* 

Tetrahedron Lett. 2015, 56, 4180-4183.  文章链接

 

 

5. Difluoromethyl 2-pyridyl sulfone: a versatile carbonyl gem-difluoroolefination reagent.

Bing Gao, Yanchuan Zhao, Jingyu Hua and Jinbo Hu* 

J. Org. Chem. Front. 2015, 2,  163-168.  文章链接

 

 

6. AgF‐Mediated Fluorinative Cross‐Coupling of Two Olefins: Facile Access to α‐CF₃ Alkenes and β‐CF₃ Ketones.

Bing Gao, Yanchuan Zhao, and Jinbo Hu* 

Angew. Chem. Int. Ed. 2015, 54 , 638-642. 文章链接

 

 

​

1. ¹⁹F NMR Fingerprints: Identification of Neutral Organic Compounds in a Molecular Container. 

Yanchuan Zhao, Georgios Markopoulos, and Timothy M. Swager* 

J. Am. Chem. Soc. 2014, 136 , 10683-10690. 文章链接

 

 

2.  Radical (2-pyridylsulfonyl)difluoromethylation of terminal alkenes with iododifluoromethyl 2-pyridyl sulfone. 

Wemjun Miao, Chuanfa Ni, Yanchuan Zhao and Jinbo Hu*  
J. Fluorine Chem. 2014, 167, 231-236. 文章链接

 

 

3. gem‐Difluoroolefination of Diaryl Ketones and Enolizable Aldehydes with Difluoromethyl 2‐Pyridyl Sulfone: New Insights into the Julia–Kocienski Reaction. 

Bing Gao, Yanchuan Zhao, Mingyou Hu, Chuanfa Ni, and Jinbo Hu* 

Chem. Eur. J. 2014, 20, 7803-7810. 文章链接

 

 

4. Selective monofluorination of active methylene compounds: the important role of ZnCl₂ in inhibiting overfluorination.

Fanzhou Jiang, Yanchuan Zhao, and Jinbo Hu* 

Org. Chem. Front. 2014, 625-629. 文章链接

 

 

1. Copper-Catalyzed Debenzoylative Monofluoromethylation of Aryl Iodides Assisted by the Removable (2-Pyridyl)sulfonyl Group. 

Yanchuan Zhao, Chuanfa Ni, Fanzhou Jiang, Bing Gao, Xiao Shen, and Jinbo Hu* 

ACS Catal. 2013, 3 , 631-634. 文章链接

 

 

 

2. Detection and Differentiation of Neutral Organic Compounds by ¹⁹F NMR with a Tungsten Calix[4]arene Imido Complex. 

Yanchuan Zhao, and Timothy M. Swager* 

J. Am. Chem. Soc. 2013, 135 , 18770-18773. 文章链接

 

 

 

3. Silver-Mediated Trifluoromethylation–Iodination of Arynes. 

Yuwen Zeng, Laijun Zhang, Yanchuan Zhao, Chuanfa Ni, Jingwei Zhao, and Jinbo Hu* 

J. Am. Chem. Soc. 2013, 135 , 2955-2958. 文章链接

 

 

 

4. DIAD-mediated metal-free cross dehydrogenative coupling between tertiary amines and α-fluorinated sulfones.  

Weizhou Huang, Chuanfa Ni, Yanchuan Zhao and Jinbo Hu* 

New J. Chem. 2013, 37 , 1684-1687. 文章链接

 

 

1. Copper-Mediated Fluoroalkylation of Aryl Iodides Enables Facile Access to Diverse Fluorinated Compounds: The Important Role of the (2-Pyridyl)sulfonyl Group. 

Yanchuan Zhao, Bing Gao, Chuanfa Ni, and Jinbo Hu* 

Org. Lett. 2012, 14 , 6080-6083. 文章链接

 

 

2. From Olefination to Alkylation: In-Situ Halogenation of Julia–Kocienski Intermediates Leading to Formal Nucleophilic Iodo- and Bromodifluoromethylation of Carbonyl Compounds. 

Yanchuan Zhao, Bing Gao, and Jinbo Hu* 

J. Am. Chem. Soc. 2012, 134 , 5790-5793. 文章链接

 

 

3. Palladium‐Catalyzed 2,2,2‐Trifluoroethylation of Organoboronic Acids and Esters. 

Yanchuan Zhao, and Jinbo Hu* 

Angew. Chem. Int. Ed. 2012, 51, 1033-1036. 文章链接

 

 

4. Palladium-catalyzed allylation of 2,2,2-trifluoroethyl phenyl sulfone, a potential 2,2,2-trifluoroethyl pronucleophile. 

Wei Zhang, Yanchuan Zhao, Chuanfa Ni, Thomas Mathew, and Jinbo Hu* 

Tetrahedron Lett. 2012, 53 , 6565-6568. 文章链接

 

 

5. Nucleophilic difluoromethylation of N,N-acetals with TMSCF₂SO₂Ph reagent promoted by trifluoroacetic acid: A facile access to α-difluoromethylated tertiary amines. 

Weizhou Huang, Chuanfa Ni, Yanchuan Zhao, Bing Gao and Jinbo Hu* 

J. Fluorine Chem. 2012, 143,  161-166. 文章链接

 

 

6. Difluoro(phenylchalcogen)methylation of aldehydes, ketones, and imines with S-, Se-, and Te-containing reagents PhXCF₂H (X = S, Se, Te). 

Mingyou Hu, Fei Wang, Zhengbiao He, Wei Zhang, and Jinbo Hu* 

J. Fluorine Chem. 2012, 135, 45-58. 文章链接 

 

 

7. Nucleophilic difluoromethylation of CN bonds in heterocycles with difluoromethyl silane reagents. 

Weizhou Huang, Chuanfa Ni, Yanchuan Zhao, Wei Zhang, Alexander D. Dilman, and Jinbo Hu* 

Tetrahedron. 2012, 68 , 5137-5144. 文章链接

 

 

1. Efficient and Direct Nucleophilic Difluoromethylation of Carbonyl Compounds and Imines with Me₃SiCF₂H at Ambient or Low Temperature. 

Yanchuan Zhao, Weizhou Huang, Ji Zheng, and Jinbo Hu* 

Org. Lett. 2011, 13 , 5342–5345. 文章链接

 

 

2. Nucleophilic Fluoromethylation of Aldehydes with Fluorobis(phenylsulfonyl) methane: The Importance of Strong Li–O Coordination and Fluorine Substitution for C–C Bond Formation. 

Xiao Shen, Laijun Zhang, Yanchuan Zhao, Guangyu Li, and Jinbo Hu* 

Angew. Chem. Int. Ed. 2011, 123 , 2636–2640. 文章链接

 

 

3. Copper-Mediated Fluoroalkylation Reactions with [(Phenylsulfonyl)-difluoro methyl] trimethylsilane: Synthesis of PhSO₂CF₂–Containing Allenes and Alkynes. 

Jieming Zhu, Fei Wang, Weizhou Huang, Yanchuan Zhao, Wenchao Ye, and Jinbo Hu* 

Synlett  2011, 7, 899–902. 文章链接

 

 

1. Difluoromethyl 2-Pyridyl Sulfone: A New gem-Difluoroolefination Reagent for Aldehydes and Ketones. 

Yanchuan Zhao, Weizhou Huang, Lingui Zhu, and Jinbo Hu* 

Org. Lett. 2010, 12 , 1444-1447. 文章链接

 

 

 

2. Magnesium Metal-Mediated Reductive Trifluoromethylation of Aldehydes with Phenyl Trifluoromethyl Sulfone. 

Yanchuan Zhao, Jieming Zhu, Chuanfa Ni, and Jinbo Hu* 

Synthesis 2010, 11,  1899-1904. 文章链接

 

 

 

3. 1-tert-Butyl-1H-tetrazol-5-yl fluoromethyl sulfone (TBTSO₂CH₂F): a versatile fluoromethylidene synthon and its use in the synthesis of monofluorinated alkenes via Julia–Kocienski olefination. 

Lingui Zhu, Chuanfa Ni, Yanchuan Zhao, and Jinbo Hu* 

Tetrahedron 2010, 66 , 5089-5100. 文章链接

 

 

4. Nucleophilic (phenylsulfonyl)difluoromethylation of alkyl halides using PhSO₂CF₂SiMe3: preparation of gem-difluoroalkenes and trifluoromethyl compounds. 

Lingui Zhu, Ya Li, Yanchuan Zhao, and Jinbo Hu* 

Tetrahedron Lett. 2010, 51 , 6150-6152. 文章链接